Do any other types of medicines, such as pain
killers, provide relief of peripheral neuropathy???
Medications mentioned as helpful (but which also tended to increase constipation) were:
Aspirin and non-steroidal anti-inflammatory drugs (NSAIDS) are usually NOT effective, especially for long term use.
Darvon (propoxyphene napsylate) and Darvoset N (contains 100 mg Darvon and 650 mg acetaminophen) are not any more effective than aspirin (ASA), but have significantly more side effects. In addition, these drugs are not recommended for use in the elderly or those with diminished kidney function, liver function, and/or heart function. (JAMA 213:996-1006, 1972; JAMA 229:55-59, 1974; American Pain Society 1999 Principles, + 10 more)
Levorphanol (Levo-Dromoran for chronic neuropathy pain: When given up to 21 capsules (0.75 mg each capsule) a day significantly reduced pain, improved sleep, and improved functioning, but caused more side effects than taking up to 21 capsules a day of the 0.15 mg capsules. However, the high strength group averaged 12 capsules daily while the low strength group averaged 18 capsules a day. (NEJM 348:1223-1232, 27 Mar 2003).
Ibuprofen and aspirin (ASA or acetylsalicylic acid) are NOT usually recommended, as they can increase the tendency to bleed.
One oncologist said he didn't feel healing could occur as effectively while his patient was hurting from neuropathy. He recommended a combination of a pin medication, Xanax for anxiety and depression, and Amitriptyline for her neuropathy and to aid her in sleeping.
Other medications which may work for some people are Dexamethosone (and other coritcosteroids), a muscle relaxant called Baclofen (Lioresal), Clonidine (Catapres), and a heart anti-arrhythmic called Mexiletine (Mexitil).
One quinine sulfate table at bedtime helped, but made the ringing in one woman's ears worse.
For relief of the itching which commonly goes along neuropathy, one woman uses hydroxyzine hydrochloride or Benadryl allergy medicine several times a day.